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GATA4 anticorps

Cet anticorps anti-GATA4 est un anticorps Lapin Polyclonal détectant GATA4 dans WB et IF. Adapté pour Humain, Rat et Souris.
N° du produit ABIN498129

Aperçu rapide pour GATA4 anticorps (ABIN498129)

Antigène

Voir toutes GATA4 Anticorps
GATA4 (GATA Binding Protein 4 (GATA4))

Reactivité

  • 84
  • 57
  • 55
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Rat, Souris

Hôte

  • 73
  • 11
  • 1
Lapin

Clonalité

  • 63
  • 22
Polyclonal

Conjugué

  • 58
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp GATA4 est non-conjugé

Application

  • 68
  • 30
  • 22
  • 19
  • 13
  • 13
  • 9
  • 7
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • Specificité

    This antibody detects endogenous levels of GATA4 protein.

    Réactivité croisée (Details)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    Purification

    Affinity chromatography using epitope-specific immunogen

    Pureté

    > 95 % (by SDS-PAGE)
  • Indications d'application

    Western blot: 1: 500 - 1: 1000. Immunoflourescence: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Antigène

    GATA4 (GATA Binding Protein 4 (GATA4))

    Autre désignation

    GATA4

    Sujet

    GATA4 is a 46 kDa member of the GATA family of zinc finger containing transcription factors that is involved in the development of cardiac hypertrophy and remodeling, and plays a critical role in regulating basal and agonist or stress induced gene expression in cardiac and smooth muscle cell types. GATA4 contains a conserved MAPK phosphorylation site at serine 105 within the transcriptional activation domain. Serine 105 of GATA4 is phosphorylated in response to agonist stimulation through MEK 1 ERK1 / 2, and weakly through JNK or p38 MAPKs.Synonyms: GATA-4, GATA-binding factor 4, Transcription factor GATA-4

    Poids moléculaire

    approx. 48 kDa

    ID gène

    2626

    NCBI Accession

    NP_002043

    UniProt

    P43694

    Pathways

    Peptide Hormone Metabolism, Carbohydrate Homeostasis
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